שאלה | In what way is current Sanger sequencing *Improved* compared to the original design?

In what way is current Sanger sequencing Improved compared to the original design?

		Originally, samples where sequenced on a flow cell with clusters of attached oligonucleotides. Now, we use oligonucleotides attached to beads in a water in oil emulsion
		Originally, samples where sequenced using oligonucleotides attached to beads in a water in oil emulsion. Now, we use 4 separate reaction mixtures, with a different ddNTP added to each
		Originally, each sample was sequenced with 4 different labled terminators in one reaction mix. Now, we use 4 separate reaction mixtures, with a different ddNTP added to each
		Originally, each sample was sequenced in 4 separate reaction mixtures, with a different ddNTP added to each. Now, 4 different labled terminators are used in one reaction mix.
		Originally, samples where sequenced using oligonucleotides attached to beads in a water in oil emulsion. Now, we use a flow cell with clusters of attached oligonucleotides.

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