שאלה | Using recombinant DNA technology to insert a 500,000 bp fragment of human genomic DNA into the genome of E. coli will likely

Using recombinant DNA technology to insert a 500,000 bp fragment of human genomic DNA into the genome of E. coli will likely

		1. cause uncontrolled DNA replication due to the multiple origins of replication added.
		2. stop DNA replication due to the inability of the prokaryotic replication machinery to recognize methylated C.
		3. kill the bacteria due to the production of a large number of foreign gene products.
		4. dramatically increase the time needed to replicate the E.coli genome due to the formation of nucleosomes.
		5. slightly increase the time needed to replicate the E.coli genome due to the extra amount of DNA.