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The TAF1 subunit of TFIID is a histone acetylase. Which of the following is the most likely consequence?

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Neurons, after they are first born, slowly start to express a neurofilament gene (NF-L) for the first time. The promoter of the NF-L gene is rich in CpG sequences. Which of the following would you expect to observe in the NF-L promoter as the gene becomes increasingly active in neurons?

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Which of the following is directed by transcription activators in eukaryotic cells such as to make DNA more accessible for the transcription machinery.

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(USMLoid) DNA methylation-induced repression of the Dapk (Death associated protein kinase) gene has been observed in 80% of colorectal carcinomas. Increased methylation of the Dapk gene most likely occurs at which of the following?

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Embryonic development and cell differentiation are largely driven by gene regulation. The most common mechanism is at which of the following levels?

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The four labelled DNA sequences are bound by proteins with sequence specific DNA-binding domains. Which one most likely binds to a PolII general transcription factor?

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(USMLoid) The protein encoded the gene ZEB1 was discovered to induce genes causing an Epithelial Mesenchymal Transition (EMT) during breast cancer tumor progression. The gene sequence and protein X-ray crystallography data showed that ZEB1 encodes a Zinc-finger motif. Which of the following is a most likely characteristic of the ZEB1 protein.

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You transfer wildtype E.coli from petri plates containing glucose to petri plates containing lactose. What sequence of events will occur at the lac operon promoter.?

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In the context of prokaryotic gene regulation, a repressor is:

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