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In the experiments of J Till and E McCulloch, ultra-violet irradiation destroyed the entire bone marrow of mice and then allogenic bone marrow cells were transplanted to these mice. Which of the below observations were presented in these studies to support the existence of bone marrow hematopoietic stem cells?

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The successful ex vivo cultivation of early embryos was an important milestone on the way to:

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What is the difference between embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs)?

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Which of the below sentences is incorrect concerning cellular reprogramming (by “Yamanaka” transcription factors versus nuclear transfer)?

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Which of the below sentences is incorrect concerning intestinal organoids culture method studied in this course?

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Which of the below sentences is incorrect regarding the difference between induced pluripotent stem cells (iPSCs) and embryonic stem cells (ESCs)?

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Which of the below sentences is incorrect concerning limbal epithelial stem cells?

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Mutations in Collagen 7 (COL7) gene lead to a severe pathology known as Epidermolysis Bullosa (EB) that affects the skin. Which of the below strategies would be suitable to model this pathology in vitro?

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Mark the incorrect statement regarding induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM):

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What are the major pathophysiological features (described in class) of induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM) generated from Duchenne muscular dystrophy (DMD) patients?

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